Microwave assisted synthesis of 5-hydroxymethylfurfural (5-HMF) over sulfonic acid anchored solid acid catalysts in isopropyl alcohol (IPA) offers specific advantages. Comparison of catalysts with different backbones stipulates a profound effect on the selectivity of fructose dehydration in IPA. The catalyst with an aliphatic backbone has a higher yield than the catalyst with a styrenic backbone. Of the tested catalyst, the DBT-ICT-Centre for Energy Biosciences, Institute of Chemical Technology Catalyst #2 (DIC_AT-2) in IPA resulted in 85% yield with >95% conversion in 120 s. The modeling analysis depicted the characteristic role of the aliphatic backbone for obtaining higher selectivity in IPA. Moreover, the use of IPA is ecologically preferred and it also facilitates product, solvent, and catalyst separation. The structural and morphological characterization with a recyclability study for five consecutive runs showed consistency in yield and conversion. The turnover number (TON), turnover frequency (TOF), E-factor, and process mass intensity (PMI) indicate an environmentally safer and industrially viable process.

中文翻译：

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DIC _A T-2：具有主干骨架的固体酸催化剂，用于在异丙醇中微波辅助合成5-羟甲基糠醛

在异丙醇（IPA）中的磺酸锚固固体酸催化剂上微波辅助合成5-羟甲基糠醛（5-HMF）具有特定的优势。比较具有不同主链的催化剂对IPA中果糖脱水的选择性产生了深远的影响。具有脂族主链的催化剂比具有苯乙烯主链的催化剂具有更高的产率。在测试过的催化剂中，化学技术研究所催化剂2（DIC _A，能源生物科学部DBT-ICT中心）IPA中的T-2）产生了85％的收率，并在120 s内转化率> 95％。建模分析描述了脂族主链在IPA中获得更高选择性的特征性作用。而且，在生态上优选使用IPA，并且它还有助于产物，溶剂和催化剂的分离。通过五个连续运行的可回收性研究对结构和形态进行了表征，结果表明收率和转化率均一致。周转数（TON），周转频率（TOF），E因子和过程质量强度（PMI）表示对环境更安全且在工业上可行的过程。