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Nanotechnology in Neuroscience Reveals Membrane Mobility Matters.
ACS Chemical Neuroscience ( IF 5 ) Pub Date : 2018-10-04 , DOI: 10.1021/acschemneuro.8b00495
Sandra J Rosenthal 1
Affiliation  

Quantum dots are nanometer-sized semiconductors that have size-tunable, narrow emission bands, high quantum yields, and are resistant to photobleaching. Ligand-conjugated quantum dots enable the real time visualization of membrane proteins and have revealed that membrane diffusion dynamics are intrinsic to protein regulation, are susceptible to the level of membrane cholesterol, and are altered in genetic variants linked to disease, suggesting a mise en place approach to neuropsychopharmacology.

中文翻译:

神经科学中的纳米技术揭示了膜的流动性。

量子点是纳米尺寸的半导体,具有尺寸可调,窄的发射带,高量子产率,并且耐光漂白。配体缀合的量子点可实现膜蛋白的实时可视化,并揭示了膜扩散动力学是蛋白调节所固有的,易受膜胆固醇水平的影响,并且在与疾病有关的遗传变异中也发生了改变,这表明发生了错配。神经心理药理学方法。
更新日期:2018-10-04
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