This study evaluated the viability of Lactobacillus rhamnosus GG (LGG) and its in vitro and in vivo resistance to the gastrointestinal tract (GIT) when carried by a mixed fermented pineapple and jussara juice. The effects of product ingestion on the biochemical characteristics of the blood and on the development of aberrant crypt foci (ACF) in Wistar rats were also determined. The LGG viability in probiotic juice was higher than 7.2 log CFU/mL throughout 28 days at 8 °C. The mean count of the probiotic microorganism in the fecal samples of the rats was 5.6 log CFU/g, identical to the count at the end of the in vitro trial (enteric phase II), indicating that the mixed pineapple and jussara juice was an excellent vehicle for LGG. No difference (p > .05) was verified to ACF among the groups. However, the results for the probiotic culture viability and its in vitro and in vivo resistance to the gastrointestinal tract suggest that this juice is an excellent carrier matrix for LGG and contributed to a reduction in the levels of the LDL (low density lipoprotein) fraction of the blood cholesterol, thus being an aid in the control of coronary diseases.

这项研究评估了鼠李糖乳杆菌GG（LGG）的生存能力以及其在发酵菠萝和果汁混合汁中的体外和体内对胃肠道（GIT）的抗性。还确定了产品摄入对Wistar大鼠血液生化特性和异常隐窝灶（ACF）发育的影响。益生菌汁液中LGG的活力在8°C的整个28天中都高于7.2 log CFU / mL。大鼠粪便样品中益生菌微生物的平均计数为5.6 log CFU / g，与体外结束时的计数相同试验（II期试验），表明菠萝和果汁混合汁是LGG的极佳载体。 各组之间ACF差异无统计学意义（p > .05）。但是，益生菌培养物活力及其对胃肠道的体外和体内抗性的结果表明，该汁液是LGG的极好载体基质，有助于降低LDL（低密度脂蛋白）部分的水平。血液中的胆固醇，因此有助于控制冠状动脉疾病。