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Synthesis of coumarins derivatives via decarboxylative cross-coupling of coumarin-3-carboxylic acid with benzylic C(sp3)-H bond
Tetrahedron Letters ( IF 1.8 ) Pub Date : 2018-10-03 , DOI: 10.1016/j.tetlet.2018.10.001
Shuang-hong Hao , Li-Xia Li , Dao-Qing Dong , Zu-Li Wang , Xian-Yong Yu

The reaction of coumarin-3-carboxylic acid with benzylic C(sp3)-H bond was established in this paper. A series of 3-benzylcoumarin derivatives were efficiently isolated in moderated to high yield using Cu(OAc)2 as catalyst and TBPB as oxidant.



中文翻译:

香豆素-3-羧酸与苄基C(sp 3)-H键的脱羧交叉偶联合成香豆素衍生物

建立了香豆素-3-羧酸与苄基C(sp3)-H键的反应。使用Cu(OAc)2作为催化剂和TBPB作为氧化剂,可以中等至高收率高效分离出一系列3-苄香豆素衍生物。

更新日期:2018-10-03
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