Two new cationic iridium(III) complexes were successfully synthesized as highly sensitive and selective phosphorescent sensors for detection of Cu²⁺ in MeOH/H₂O (1:1) solution and in living cells. These cationic Ir(III) complexes were prepared by reactions of two different Ir(III) chloro-bridged dimers with 2,2′-dipyridine tethered DPA (di(2-picolyl)amine) moiety as the ancillary ligand. These phosphorescent sensors displayed significant reversible phosphorescence quenching upon binding to Cu²⁺ ions with a 10 ppb detection limit. They had strong binding ability with Cu²⁺ ions and the binding ratios were approximately 1:1, and also exhibited good cell permeability and good imaging characteristics in detecting Cu²⁺ ions in living cells. It is worth mentioning that one of the phosphorescent sensors is almost nontoxic to Hela cells, indicating that it greatly increases the possibility of application in biochemistry.

成功地合成了两种新型的阳离子铱（III）络合物，作为高灵敏度和选择性磷光传感器，用于检测MeOH / H ₂ O（1：1）溶液和活细胞中的Cu ²⁺。这些阳离子Ir（III）配合物是通过两个不同的Ir（III）氯桥联二聚体与2,2'-联吡啶的DPA（di（2-picolyl）amine）部分作为辅助配体反应而制备的。这些磷光传感器在以10 ppb的检测限结合到Cu ²⁺离子后，显示出可逆的显着磷光猝灭。它们与Cu ²⁺离子具有很强的结合能力，结合比约为1：1，并且在检测Cu ^2+时具有良好的细胞渗透性和良好的成像特性。活细胞中的离子。值得一提的是，其中一种磷光传感器对Hela细胞几乎无毒，这表明它大大增加了在生物化学中应用的可能性。