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Long‐Term Supplementation of Black Elderberries Promotes Hyperlipidemia, but Reduces Liver Inflammation and Improves HDL Function and Atherosclerotic Plaque Stability in Apolipoprotein E‐Knockout Mice
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2018-10-19 , DOI: 10.1002/mnfr.201800404
Courtney L. Millar 1 , Gregory H. Norris 1 , Christina Jiang 1 , James Kry 1 , Addison Vitols 1 , Chelsea Garcia 1 , Young‐Ki Park 1 , Ji‐Young Lee 1 , Christopher N. Blesso 1
Affiliation  

HDL particles are protective against atherosclerosis, but may become dysfunctional during inflammation and chronic disease progression. Anthocyanin‐rich foods, such as the black elderberry, may improve HDL function and prevent disease development via antioxidant and/or anti‐inflammatory effects. This study investigates the long‐term consumption of black elderberry extract (BEE) on HDL function and atherosclerosis in apolipoprotein (apo) E−/− mice.

中文翻译:

长期补充黑接骨木浆果可促进高脂血症,但减少载脂蛋白E基因敲除小鼠的肝脏炎症并改善HDL功能和动脉粥样硬化斑块稳定性

HDL颗粒可预防动脉粥样硬化,但在炎症和慢性疾病发展过程中可能会出现功能障碍。富含花青素的食物,例如黑接骨木浆果,可通过抗氧化剂和/或抗炎作用改善HDL功能并预防疾病发展。这项研究调查了长期摄取黑接骨木提取物(BEE)对载脂蛋白(apo)E -/-小鼠的HDL功能和动脉粥样硬化。
更新日期:2018-10-19
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