Affecting 5% of all preschool-aged children and 1% of the general population, developmental stuttering-also called childhood-onset fluency disorder-is a complex, multifactorial neurodevelopmental disorder characterized by frequent disruption of the fluent flow of speech. Over the past two decades, neuroimaging studies of both children and adults who stutter have begun to provide significant insights into the neurobiological bases of stuttering. This review highlights convergent findings from this body of literature with a focus on functional and structural neuroimaging results that are supported by theoretically driven neurocomputational models of speech production. Updated views on possible mechanisms of stuttering onset and persistence, and perspectives on promising areas for future research into the mechanisms of stuttering, are discussed.

中文翻译：

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口吃的功能和神经解剖学基础：最新见解。

影响所有学龄前儿童的5％和总人口的1％，发展性口吃-也称为童年发作的流利性障碍-是一种复杂的，多因素的神经发育障碍，其特征是频繁地中断流利的言语交流。在过去的二十年中，对口吃的儿童和成人的神经影像学研究已经开始提供有关口吃的神经生物学基础的重要见解。这篇综述着重介绍了这一文献的聚合发现，重点是功能性和结构性神经影像学结果，这些结果得到了语音产生的理论驱动的神经计算模型的支持。讨论了有关口吃发作和持续性可能机制的最新观点，以及有关口吃机制未来研究的有希望领域的观点。