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Signals from single molecules
Nature Reviews Chemistry ( IF 36.3 ) Pub Date : 2018-09-27 , DOI: 10.1038/s41570-018-0045-3
Stephen G. Davey

Signals from single molecules

Signals from single molecules, Published online: 27 September 2018; doi:10.1038/s41570-018-0045-3

Following binding kinetics over time rather than relying on differences in free-energy of binding enables detection of single molecules of mutant DNA with an estimated specificity of 99.99999%.


中文翻译:

来自单分子的信号

来自单分子的信号

来自单分子的信号,在线发布:2018年9月27日; doi:10.1038 / s41570-018-0045-3

随时间变化的结合动力学(而不是依赖于结合自由能的差异)使检测突变型DNA的单个分子的估计特异性达到99.99999%。
更新日期:2019-01-26
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