Mn–Fe layered double hydroxide nanosheets: a new photothermal nanocarrier for O2-evolving phototherapy†,Chemical Communications

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Mn–Fe layered double hydroxide nanosheets: a new photothermal nanocarrier for O2-evolving phototherapy†
Chemical Communications ( IF 4.9 ) Pub Date : 2018-09-26 00:00:00 , DOI: 10.1039/c8cc06033a
Yudi Ruan _{1,

2,

3,

4,

5} , Xiaodai Jia _{1,

2,

3} , Chao Wang _{1,

2,

3,

6,

7} , Wenyao Zhen _{1,

2,

3,

6,

7} , Xiue Jiang _{1,

2,

3,

4,

5}

Affiliation

Iron–manganese layered double hydroxide nanosheets were developed as an effective photothermal nanocarrier for loading a photosensitizer. The catalase-like activity enables the nanosheets to decompose H₂O₂ into O₂, overcoming tumor hypoxia and enhancing O₂-dependent photodynamic therapy (PDT). The combination of PDT and photothermal therapy (PTT) can almost completely eliminate tumor tissues.

中文翻译：

Mn-Fe层状双氢氧化物纳米片：用于O ₂演变的光疗的新型光热纳米载体†

铁锰层状双氢氧化物纳米片被开发为有效的光热纳米载体，用于装载光敏剂。过氧化氢酶样活性使纳米片能够将H ₂ O ₂分解为O ₂，克服了肿瘤的缺氧并增强了O ₂依赖性光动力疗法（PDT）。PDT与光热疗法（PTT）的结合几乎可以完全消除肿瘤组织。

更新日期：2018-09-26

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