AbstractA molecularly imprinted polymer (MIP) was fabricated for selective recognition of the highly persistent pollutant perfluorooctane sulfonate (PFOS). The MIP was prepared from chitosan and doped with fluorescent carbon quantum dots (CQDs). It was characterized by fluorescence spectrophotometry, scanning electron microscopy, and Fourier transform infrared spectroscopy. The fluorescence of the CQDs, best measured at excitation/emission wavelengths of 350/460 nm, is enhanced by PFOS, and the effect is much stronger for the MIP than for the nonimprinted polymer (NIP). The imprinting factor is 2.75. The method has good specificity over sodium dodecyl sulfate (SDS), perfluorooctanoic acid (PFOA), sodium dodecyl sulfonate (SDS’), sodium dodecyl benzene sulfonate (SDBS), perfluorooctanesulfonyl fluoride (POSF), perfluorobutane sulfonate (PFBS) and 1-octanesulfonic acid sodium (OSA). Fluorescence increases linearly in the 20–200 pg·L−1 POSF concentration range in aqueous solution. The method was applied to the determination of PFOS in spiked serum and urine samples. The limits of detection are 66 and 85 pg·L−1 for serum and urine samples respectively. The recoveries ranged from to 81–98%, with relative standard deviations in the range of 1.8–8.2%. Compared with LC-MS/MS, this assay is more convenient since the material can be prepared flexibly and the method can be applied on-site. Graphical abstractSchematic of the fabrication of a molecularly imprinted chitosan hydrogel doped with CQDs for selective fluorometric determination of PFOS. a. The photo of chitosan hydrogel. b, c, d, e represents the hydrogel observed under UV lamp. b’, c’, d’, e’ represents the inner structure of hydrogel bead.

中文翻译：

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一种掺杂碳量子点的分子印迹壳聚糖用于全氟辛烷磺酸的荧光测定

摘要 制备了一种分子印迹聚合物 (MIP)，用于选择性识别高持久性污染物全氟辛烷磺酸 (PFOS)。MIP 由壳聚糖制备并掺杂有荧光碳量子点 (CQD)。通过荧光分光光度法、扫描电子显微镜和傅里叶变换红外光谱对其进行表征。CQD 的荧光最好在 350/460 nm 的激发/发射波长下测量，PFOS 增强了它的荧光，MIP 的效果比非印迹聚合物 (NIP) 强得多。印记因子是 2.75。该方法对十二烷基硫酸钠 (SDS)、全氟辛酸 (PFOA)、十二烷基磺酸钠 (SDS')、十二烷基苯磺酸钠 (SDBS)、全氟辛烷磺酰氟 (POSF)、全氟丁烷磺酸 (PFBS) 和 1-辛烷磺酸钠 (OSA)。荧光在水溶液中 20–200 pg·L-1 POSF 浓度范围内线性增加。该方法用于测定加标血清和尿液样品中的 PFOS。血清和尿液样品的检测限分别为 66 和 85 pg·L-1。回收率范围为 81-98%，相对标准偏差范围为 1.8-8.2%。与 LC-MS/MS 相比，该检测方法更方便，因为材料可以灵活制备，并且该方法可以现场应用。用于选择性荧光测定全氟辛烷磺酸的掺杂 CQD 的分子印迹壳聚糖水凝胶的制备示意图。一种。壳聚糖水凝胶的照片。b、c、d、e 代表在紫外灯下观察到的水凝胶。b', c', d',