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An efficient synthesis of triazolium ion based NHC precursors using diaryliodonium salts and their photophysical properties
Organic & Biomolecular Chemistry ( IF 3.2 ) Pub Date : 2018-09-21 , DOI: 10.1039/c8ob01818a
Meenakshi Pilania 1, 1, 2, 3, 4 , Mostofa Ataur Rohman 1, 4, 5, 6 , V. Arun 1, 2, 3, 4 , Manish Kumar Mehra 1, 2, 3, 4 , Sivaprasad Mitra 1, 4, 5, 6 , Dalip Kumar 1, 2, 3, 4
Affiliation  

Copper-catalysed N-arylation of fused triazoles using diaryliodonium salts as an aryl source is described. This scalable protocol displayed good compatibility towards diverse sensitive functional groups like ester, alkyl and nitro groups and halogens (F, Cl, Br). The synthetic usefulness of the prepared triazolium salts was proved by preparing α-hydroxyketone through benzoin condensation. Photophysical studies of these compounds showed promising Stokes-shifted fluorescence emission in aqueous medium, so this molecular framework could be a proficient probe for biological applications.

中文翻译:

利用二芳基碘鎓盐有效合成三唑鎓离子基NHC前体及其光物理性质

描述了使用二芳基碘鎓盐作为芳基源的铜催化的稠合三唑的N-芳基化。这种可扩展的协议显示出对各种敏感官能团(如酯,烷基和硝基基团以及卤素(F,Cl,Br))的良好兼容性。通过安息香缩合制备α-羟基酮,证明了所制备的三唑鎓盐的合成有用性。这些化合物的光物理研究表明,在水性介质中有希望的斯托克斯位移荧光发射,因此该分子框架可能是生物学应用的有效探针。
更新日期:2018-10-18
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