There is growing evidence that whole grain (WG) intake may prevent many chronic diseases. However, there are mixed results on this topic in human studies as a result of a lack of accurate tools to assess the intake of WGs and individual metabolic variation. To better understand the effects of WGs on health maintenance and the risk of chronic disease, there is an urgent need to identify the biomarkers for WG intake. The molecular signatures of WG intake remain undefined. This perspective gives an overview of the current knowledge, challenges, and future directions on the biomarkers of WG intake.

中文翻译：

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全谷物摄入量的生物标志物

越来越多的证据表明，摄入全谷物（WG）可以预防许多慢性疾病。但是，由于缺乏评估WGs摄入量和个体代谢变化的准确工具的结果，在人类研究中有关该主题的结果参差不齐。为了更好地了解工作组对健康维护和慢性病风险的影响，迫切需要确定工作组摄入的生物标志物。WG摄入的分子特征仍然不确定。该观点概述了WG摄入生物标志物的当前知识，挑战和未来方向。