Hydroxyapatite (Ca₁₀(PO₄)₆(OH)₂, HA) is chemically similar to the mineral component of bones and hard tissues in mammals. Various cations can substitute calcium in the crystal structure of hydroxyapatite. Among them strontium triggers interest, because strontium incorporated hydroxyapatite increases the number of bone forming sites in addition to having good biocompatibility

In the present investigation strontium substituted hydroxyapatite (SHA) in the compositions range 0, 10, 20, 50 and 100 mol% have been synthesized by precipitation method and subjected to ultrasonic treatment for different time intervals to gain insight on the role of ultrasound in modifying the morphology of SHA. This study reveals that the aspect ratio of SHA varied with the duration of ultrasonication. SHA samples subjected to 5 min ultrasound experienced an increase in aspect ratio. Further increase of ultrasonication time tends to decrease the aspect ratio invariably for all SHA samples indicating particle fragmentation. The extent of sonofragmentation as a function of percentage incorporation of strontium in HA lattice has been studied as a part of the present investigation. This study indicated that strain in the HA lattice has correlation with strontium incorporation, leading to varied extent of sonofragmentation. Also, the investigation suggested that 100% substitution of calcium sites by strontium leads to a relatively lesser strain and hence poor fragmentation. To the best of our knowledge the report on sonofragmentation of HA crystallites as a function of strontium incorporation is first of its kind in the literature.

羟基磷灰石（Ca ₁₀（PO ₄）₆（OH）₂，HA）在化学上与哺乳动物骨骼和硬组织的矿物质成分相似。各种阳离子可以取代羟磷灰石晶体结构中的钙。其中锶引起人们的兴趣，因为掺锶的羟基磷灰石除了具有良好的生物相容性外，还增加了骨形成部位的数量。

在本研究中，已通过沉淀法合成了组成为0、10、20、50和100 mol％的锶取代羟基磷灰石（SHA），并对其进行了不同时间间隔的超声处理，以了解超声在改性中的作用。 SHA的形态。这项研究表明，SHA的纵横比随超声持续时间而变化。经受5分钟超声的SHA样品的长宽比有所增加。对于所有表明颗粒破碎的SHA样品，超声时间的进一步增加趋向于不变地降低长宽比。作为本研究的一部分，已经研究了声碎的程度与锶在HA晶格中的掺入百分比的关系。这项研究表明，HA晶格中的应变与锶的掺入有关，导致不同程度的声碎。同样，研究表明，锶将钙位点100％置换会导致相对较小的应变，从而导致碎片变差。据我们所知，关于HA微晶的声碎作用作为锶掺入函数的报道在文献中尚属首次。