Stimuli-responsive biomaterials, capable of responding on-demand to changes in their local environment, have become a subject of interest in the field of regenerative medicine. Magneto-responsive biomaterials, which can be manipulated spatiotemporally via an external magnetic field, have emerged as promising candidates as active scaffolds for advanced drug delivery and tissue regeneration applications. These specialized biomaterials can be synthesized by physically and/or chemically incorporating magnetic nanoparticles into the biomaterial structure. However, despite their promising impact on the future of regenerative medicine, magneto-responsive biomaterials still have several limitations that need to be overcome before they can be implemented clinically in a reliable manner, as predicting their behavior and biocompatibility remains an ongoing challenge. This review article will focus on discussing the current fabrication methods used to synthesize magneto-responsive materials, efforts to predict and characterize magneto-responsive biomaterial behavior, and the application of magneto-responsive biomaterials as controlled drug delivery systems, tissue engineering scaffolds, and artificial muscles.

能够对本地环境变化按需做出响应的刺激响应性生物材料已经成为再生医学领域的关注主题。可以通过外部磁场在时空上进行操纵的磁响应生物材料已成为有前途的候选材料，成为用于先进药物输送和组织再生应用的活性支架。这些专门的生物材料可以通过将磁性纳米颗粒物理和/或化学结合到生物材料结构中来合成。但是，尽管它们对再生医学的未来产生了令人鼓舞的影响，但磁响应生物材料仍存在一些局限性，需要加以克服，然后才能以可靠的方式将其临床应用，因为预测它们的行为和生物相容性仍然是一个持续的挑战。这篇评论文章将重点讨论用于合成磁响应材料的当前制​​造方法，预测和表征磁响应生物材料行为的努力，以及磁响应生物材料作为受控药物输送系统，组织工程支架和人工材料的应用。肌肉。