Nanoscale zero-valent iron (nZVI) has been recognized as one of the most promising materials for the removal of a wide range of pharmaceuticals in water; however, aggregation and instability of nZVI in aqueous media reduces its efficacy. In this study, graphene oxide (GO) supported nZVI/copper bimetallic-nanoparticles (BNPs) were fabricated for high-efficiency removal of tetracyclines (TCs). In comparison to pure nZVI, the addition of Cu to the nano-adsorbents enhanced the efficacy of TC removal by 13%. The GO supporter mitigated the aggregation of BNPs and reduced the dissolution of metal nanoparticles, thereby demonstrating a higher working efficacy than Fe/Cu BNPs, even over five consecutive runs. At the optimal condition (pH 5–7, [TCs]: [Fe/Cu-GO] = 1:2.5 w/w), the Fe/Cu-GO nanocomposite showed near-complete (∼100%) TCs-removal within 15 min. The adsorption of TCs by Fe/Cu-GO fits the Freundlich model, with an adsorption capacity of 201.9 mg g⁻¹. The Fe/Cu-GO nanocomposite showed pH-dependent assembly behavior to potentially recycle GO at a pH > 9 condition to generate new nanoparticles. The high removal efficiency of TCs, combining with high stability and easy separation performance in the aqueous environment, makes Fe/Cu-GO nanocomposites a promising material for treating latent antibiotics in water.

纳米零价铁（nZVI）被公认为是去除水中多种药物的最有前途的材料之一。然而，nZVI在水性介质中的聚集和不稳定性降低了其功效。在这项研究中，氧化石墨烯（GO）负载的nZVI /铜双金属纳米颗粒（BNPs）可以高效去除四环素（TCs）。与纯nZVI相比，向纳米吸附剂中添加Cu将TC去除的功效提高了13％。GO支撑剂减轻了BNP的聚集并减少了金属纳米颗粒的溶解，因此即使在连续运行五次后，也显示出比Fe / Cu BNP更高的工作效率。在最佳条件下（pH 5-7，[TCs]：[Fe / Cu-GO] = 1：2.5 w / w），Fe / Cu-GO纳米复合材料在TCs去除率接近完全（〜100％）。 15分钟^-1。Fe / Cu-GO纳米复合材料表现出pH依赖的组装行为，可以在pH> 9的条件下循环利用GO生成新的纳米颗粒。TCs的高去除效率，再加上在水性环境中的高稳定性和易于分离的性能，使得Fe / Cu-GO纳米复合材料成为治疗水中潜在抗生素的有前途的材料。