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Lactobacillus acidophilus Alleviated Salmonella‐Induced Goblet Cells Loss and Colitis by Notch Pathway
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2018-09-21 , DOI: 10.1002/mnfr.201800552
Haiqin Wu 1 , Lulu Ye 1 , Xiaoxi Lu 1 , Shuang Xie 1 , Qian Yang 1 , Qinghua Yu 1
Affiliation  

The intestinal mucosal barrier, including the mucus layer, protects against invasion of enteropathogens, thereby inhibiting infection. In this study, the protective effect of Lactobacillus on the intestinal barrier against Salmonella infection is investigated. The underlying mechanism of its effect, specifically on the regulation of goblet cells through the Notch pathway, is also elucidated.

中文翻译:

嗜酸乳杆菌通过缺口途径减轻沙门氏菌诱导的杯状细胞丢失和结肠炎

包括粘液层在内的肠粘膜屏障可防止肠病原体的侵袭,从而抑制感染。在这项研究中,研究了乳酸菌对肠沙门氏菌感染的肠屏障的保护作用。还阐明了其作用的潜在机制,特别是对通过Notch途径调节杯状细胞的作用。
更新日期:2018-09-21
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