The objective of this Account is to summarize the first five years of anion−π catalysis. The general idea of anion−π catalysis is to stabilize anionic transition states on aromatic surfaces. This is complementary to the stabilization of cationic transition states on aromatic surfaces, a mode of action that occurs in nature and is increasingly used in chemistry. Anion−π catalysis, however, rarely occurs in nature and has been unexplored in chemistry. Probably because the attraction of anions to π surfaces as such is counterintuitive, anion−π interactions in general are much younger than cation−π interactions and remain under-recognized until today. Anion−π catalysis has emerged from early findings that anion−π interactions can mediate the transport of anions across lipid bilayer membranes. With this evidence for stabilization in the ground state secured, there was no reason to believe that anion−π interactions could not also stabilize anionic transition states.

中文翻译：

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阴离子-π催化的出现

该帐户的目的是总结阴离子-π催化的前五年。阴离子-π催化的一般思想是稳定芳香族表面上的阴离子过渡态。这是对芳香族表面上阳离子过渡态稳定的补充，后者是自然界发生的一种作用方式，在化学中越来越多地使用。然而，阴离子-π催化在自然界中很少发生，并且在化学上还没有被探索。可能是因为阴离子本身对π表面的吸引是违反直觉的，所以阴离子-π相互作用通常比阳离子-π相互作用年轻得多，直到今天仍未得到充分认识。阴离子-π催化作用已从早期发现中发现，阴离子-π相互作用可介导阴离子跨脂质双层膜的转运。