A Rh(III)-catalyzed C–H activation of indole at the C4-position leading to novel and switchable functionalization has been reported by employing a weakly co-ordinating COCF₃ group as a directing group. An additive plays an important role in switching the selectivity between 1,4-addition products and Heck-type products. An acid additive led to the formation of 1,4-addition products whereas a base additive promotes the formation of Heck-type products. Deuteration studies and control experiments were helpful to propose the mechanism.

中文翻译：

---

铑（iii）催化的吲哚C4位上的C–H活化：马来酰亚胺的可切换的氢芳基化和氧化性Heck型反应†

通过弱配位的COCF ₃基团作为指导基团，已报道了Rh（III）催化的C4-位吲哚在CH4上的CH活化，从而导致新颖且可转换的官能化。添加剂在1，4-加成产物和Heck型产物之间切换选择性方面起着重要作用。酸添加剂导致形成1,4-加成产物，而碱添加剂则促进形成Heck型产物。氘代研究和控制实验有助于提出机理。