Liquid-liquid equilibrium data for systems based on acetonitrile + polyvinylpyrrolidone (PVP) (10000, 29000 and 40000 g·mol⁻¹) + water were experimentally measured at 298.15 ± 1.00 K and 0.1 ± 0.01 MPa. Merchuck’s empirical equation was correlated with experimental binodal data, and the tie-lines and critical points (PCs) to complete the phase diagrams were determined. In both phases, the content of acetonitrile is high (>50 wt%), as the top-phase is rich in water while the bottom phase is rich in PVP. The systems were used in the partitioning of three phenolic compounds (here used as standard biomolecules). Cyanidin-3-O-glucoside chloride migrated preferentially to the top phase while gallic acid and quercetin migrated to the PVP-rich phase. The system formed by acetonitrile (ACN) (62.05 wt%) + PVP-10000 (12.05 wt%) + H₂O (25.90 wt%) was more selective for the separation of cyanidin-3-O-glucoside chloride from gallic acid (S_CYA/AGA = 65.41) and quercetin (S_CYA/QUE = 42.77).

基于乙腈+聚乙烯吡咯烷酮（PVP）的系统的液-液平衡数据（10000、29000和40000 g·mol ^-1）+水的实验测量值为298.15±1.00 K和0.1±0.01 MPa。将Merchuck的经验方程与实验二项式数据相关联，并确定完成相图的联系线和临界点（PC）。在两个相中，乙腈的含量都很高（> 50 wt％），因为上层相富含水，而下层相富含PVP。该系统用于三种酚类化合物（在此用作标准生物分子）的分配。Cyanidin-3-O-葡萄糖苷氯化物优先迁移至顶相，而没食子酸和槲皮素则迁移至富含PVP的相。由乙腈（ACN）（62.05 wt％）+ PVP-10000（12.05 wt％）+ H ₂ O（25.90 wt％）形成的系统对于从没食子酸中分离花青素3-O-葡萄糖苷氯化物（小号_{CYA / AGA}  = 65.41）和槲皮素（S _{CYA / QUE}  = 42.77）。