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Superhydrophobic Polyhydroxyalkanoates: Preparation and Applications.
Biomacromolecules ( IF 6.2 ) Pub Date : 2018-09-18 , DOI: 10.1021/acs.biomac.8b01176
Xue-Mei Che , Dai-Xu Wei , Guo-Qiang Chen

Poly( R-3-hydroxybutyrate- co- R-3-hydroxyhexanoate) (PHBHHx), a family member of microbial polyhydroxyalkanoates (PHA), is a biodegradable and biocompatible material with some hydrophobicity and reasonable strength for packaging and tissue engineering applications. In this study, superhydrophobic PHBHHx is fabricated via a simple nonsolvent-assisted process. The material can absorb all tested hydrophobic solvents and oil up to 6-fold of the material weights from water, permitting applications for cleaning environmental oil or solvent pollutions with convenience of disposal after the usage due to its biodegradability. With an excellent combination of biodegradability and biocompatibility, superhydrophobic PHBHHx films are evaluated for antibioadhesion properities to exploit possible implant usages. Up to 100% reductions for platelet adhesions on the superhydrophobic PHBHHx surfaces are observed compared with that on the control material surfaces. Superhydrophobic biodegradable and biocompatible PHBHHx films demonstrate promising low value and high volume or high value and low volume applications.

中文翻译:

超疏水性聚羟基链烷酸酯:制备与应用。

聚(R-3-羟基丁酸酯-R-3-羟基己酸酯)(PHBHHx)是微生物聚羟基链烷酸酯(PHA)的家族成员,是一种可生物降解和生物相容的材料,具有一定的疏水性和合理的强度,适用于包装和组织工程应用。在这项研究中,超疏水PHBHHx是通过简单的无溶剂辅助工艺制备的。该材料可从水中吸收所有经过测试的疏水性溶剂和油,最多是材料重量的6倍,由于其可生物降解性,因此可用于清洁环境中的油或溶剂污染,使用后易于处置。通过将生物降解性和生物相容性完美结合,对超疏水PHBHHx膜的抗生物粘附性进行了评估,以开发可能的植入物用途。与对照材料表面相比,超疏水PHBHHx表面的血小板粘附降低了100%。超疏水的可生物降解和生物相容性PHBHHx膜具有广阔的应用前景,包括低价值和高产量。
更新日期:2018-09-05
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