Purpose: Despite the use of fluorescence-guided surgery (FGS), maximum safe resection of glioblastoma multiforme (GBM) remains a major challenge. It has restricted surgeons between preoperative diagnosis and intraoperative treatment. Currently, an integrated approach combining preoperative assessment with intraoperative guidance would be a significant step in this direction.

中文翻译：

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使用⁶⁸ Ga-IRDye800CW-BBN在胶质母细胞瘤中进行PET和光学双模态图像引导手术的首次人体研究

目的：尽管使用了荧光引导手术（FGS），但最大程度安全切除多形性胶质母细胞瘤（GBM）仍然是一项重大挑战。它限制了术前诊断和术中治疗之间的内科医生。目前，将术前评估与术中指导相结合的综合方法将是朝着这个方向迈出的重要一步。