Porous titanium scaffolds with different unit cell type (tetrahedron and octahedron) and pore size (500 µm and 1000 µm) were fabricated by selective laser melting (SLM), and the effects of unit cell type and pore size on their fatigue properties and cell affinity were studied. The fatigue properties were performed by static and dynamic mechanical testing, while the cell affinity was evaluated in vitro with mouse osteoblast cells. It was found that octahedron scaffolds exhibited superior static mechanical properties, longer fatigue lives and higher fatigue strength in comparison to those of tetrahedron ones. As expected, scaffolds with 1000 µm pore resulted in lower compressive properties and shorter fatigue lives compared to those with 500 µm pore. The differences were analyzed based on the unit cell structure, porosity, and manufacturing imperfections. Scanning electron microscopy (SEM) and immunofluorescence showed that cells spread better on octahedron scaffolds than those on tetrahedron ones. Meanwhile, the scaffolds with 1000 µm pore were more suitable for cell attachment and growth within the same unit cell owing to higher porosity. The comparison of different pore geometry on the mechanical and biological property provided further insight into designing an optimal porous scaffold.

通过选择性激光熔化（SLM）制备了具有不同晶胞类型（四面体和八面体）和孔径（500 µm和1000 µm）的多孔钛支架，以及晶胞类型和孔径对其疲劳性能和细胞亲和力的影响被研究了。疲劳性能通过静态和动态机械测试进行，而细胞亲和力则在体外用小鼠成骨细胞进行评估。发现与四面体支架相比，八面体支架表现出优异的静态机械性能，更长的疲劳寿命和更高的疲劳强度。正如预期的那样，与具有500 µm孔隙的支架相比，具有1000 µm孔隙的支架导致较低的压缩性能和较短的疲劳寿命。根据晶胞结构，孔隙率，和制造缺陷。扫描电子显微镜（SEM）和免疫荧光显示，八面体支架上的细胞比四面体支架上的细胞扩散更好。同时，由于孔隙率较高，具有1000 µm孔的支架更适合在同一晶胞内附着和生长。对不同的孔几何形状的机械和生物学性质的比较为设计最佳的多孔支架提供了进一步的见识。