A protocol for the carboxylation of diamines employing quaternary ammonium hydrogen carbonates as C1 source is presented. The approach is used to obtain industrially relevant bis-O-alkyl carbamates with diverse structural features in very high yield, even on gram scale. The quaternary ammonium salts, formally acting as “transporters” of the carboxylating agent, can be recovered after the reaction, and recycled with high efficiency. Regeneration of the hydrogen carbonates on ion-exchange resin grants excellent atom economy in the process.

中文翻译：

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碳酸氢盐对二胺的可持续羧化

提出了使用碳酸氢铵季铵作为C1源进行二胺羧化的方案。该方法被用于以非常高的产率，甚至以克规模获得具有各种结构特征的工业上相关的双-O-烷基氨基甲酸酯。正式用作羧化剂“转运体”的季铵盐可以在反应后回收，并可以高效回收。在离子交换树脂上再生碳酸氢盐可在此过程中实现出色的原子经济性。