An overview is given on the state-of-the-art in synthesis of sequence-controlled and sequence-defined oligomers and polymers. These materials constitute chains in which chemical information is encoded along the backbone either as multiblock copolymers (controlled) or as monodisperse sequences of single monomers (defined). Focus is placed on reversible-deactivation radical polymerization techniques as these give access to a broad variety of chemical functionalities and allow for simple and fast synthesis procedures. Sequence-controlled and -defined materials have the ability to re-shape materials chemistry due to their close resemblance to biopolymers regarding structural uniformity. The field is at the edge of being able to start exploring the distinct properties that such synthetic macromolecules may have.

中文翻译：

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受控聚合的序列定义：下一代材料

概述了序列控制和序列定义的低聚物和聚合物的合成技术。这些材料构成链，其中化学信息沿着主链编码为多嵌段共聚物（受控）或单个单体的单分散序列（定义为）。重点放在可逆失活自由基聚合技术上，因为这些技术可提供广泛的化学功能，并允许简单而快速的合成程序。由于顺序控制和定义的材料在结构均匀性方面与生物聚合物非常相似，因此它们具有重塑材料化学性质的能力。该领域处于能够开始探索这种合成大分子可能具有的独特特性的边缘。