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Mechanical properties, in vitro corrosion resistance and biocompatibility of metal injection molded Ti-12Mo alloy for dental applications
Journal of the Mechanical Behavior of Biomedical Materials ( IF 3.9 ) Pub Date : 2018-08-28 , DOI: 10.1016/j.jmbbm.2018.08.038
W. Xu , X. Lu , L.N. Wang , Z.M. Shi , S.M. Lv , M. Qian , X.H. Qu

A biocompatible Ti-12Mo alloy was fabricated by metal injection moulding (MIM) using non-spherical titanium, molybdenum powders and a purposely designed binder. The density, microstructure and tensile properties were characterized. This was followed by a detailed assessment of its in vitro corrosion and biocompatibility performances, compared with that of two commonly used titanium-based materials extra low interstitial (ELI) Ti-6Al-4V and commercially pure (CP) titanium. The MIM-fabricated Ti-12Mo alloy can achieve a wide range of mechanical properties through controlling sintering process. Specimens sintered at 1400 °C are characterized by fairly uniform near-β microstructure and high relative density of 97.6%, leading to the highest tensile strength of 845.3 ± 21 MPa and elongation of 4.15 ± 0.2% while the highest elastic modulus of 73.2 ± 5.1 GPa. Owing to the formation of protective TiO2-MoO3 passive film, the MIM-fabricated Ti-12Mo alloy exhibits the highest corrosion resistance including the noblest corrosion potential, the lowest corrosion current density and the highest pitting potential in four different electrolytes. The in vitro cytotoxicity test suggests that the MIM-fabricated Ti-12Mo alloy displays no adverse effect on MC3T3-E1 cells with cytotoxicity ranking of 0 grade, which is nearly close to ELI Ti-6Al-4V or CP Ti. These properties together with its easy net-shape manufacturability make Ti-12Mo an attractive new dental implant alloy.



中文翻译:

牙科用金属注射成型的Ti-12Mo合金的机械性能,体外耐腐蚀性和生物相容性

生物相容性Ti-12Mo合金是通过使用非球形钛,钼粉和专门设计的粘合剂的金属注射成型(MIM)制成的。表征了密度,微观结构和拉伸性能。与两种常用的超低间隙(ELI)Ti-6Al-4V和商业纯(CP)钛基钛材料相比,随后对其详细的体外腐蚀和生物相容性性能进行了评估。MIM制造的Ti-12Mo合金可通过控制烧结过程获得广泛的机械性能。在1400°C下烧结的试样的特征是:相当均匀的近β微观结构和97.6%的高相对密度,导致最高抗拉强度为845.3±21 MPa,伸长率为4.15±0.2%,而最高弹性模量为73.2±5 。1 GPa。由于形成保护性TiOMIM制造的Ti-12Mo合金2 -MoO 3钝化膜在四种不同的电解质中具有最高的耐腐蚀性,包括最高的腐蚀电位,最低的腐蚀电流密度和最高的点蚀电位。体外细胞毒性试验表明,MIM制备的Ti-12Mo合金对MC3T3-E1细胞没有不良影响,细胞毒性等级为0级,几乎接近ELI Ti-6Al-4V或CP Ti。这些特性及其易于制造的网状形状使Ti-12Mo成为一种有吸引力的新型牙科植入物合金。

更新日期:2018-08-28
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