当前位置: X-MOL 学术Bioorgan. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Trichocarotins A–H and trichocadinin A, nine sesquiterpenes from the marine-alga-epiphytic fungus Trichoderma virens
Bioorganic Chemistry ( IF 5.1 ) Pub Date : 2018-08-27 , DOI: 10.1016/j.bioorg.2018.08.027
Zhen-Zhen Shi , Sheng-Tao Fang , Feng-Ping Miao , Xiu-Li Yin , Nai-Yun Ji

In addition to CAF-603, 14-hydroxy CAF-603 (trichocarane B), 7-β-hydroxy CAF-603, and trichocarane A, eight new carotane sesquiterpenes, trichocarotins A–H, and one new cadinane sesquiterpene, trichocadinin A, were isolated from the culture of Trichoderma virens Y13-3, obtained from the surface of a marine red alga. Their structures and relative configurations were unambiguously assigned by interpretation of 1D/2D NMR and MS data, and their absolute configurations were established by X-ray diffraction or ECD spectra aided by quantum chemical calculations. These compounds represent two rarely occurring sesquiterpene types from filamentous fungi, and six of them feature potent inhibition against some marine plankton species.



中文翻译:

Trichocarotins A–H和trichocadinin A,来自海藻表生真菌木霉属的九种倍半萜

除了CAF-603、14-羟基CAF-603(三氯甲烷B),7-β-羟基CAF-603和甲虫三环烷A外,还有八种新的胡萝卜素倍半萜,三氯胡萝卜素A–H和一种新的卡丁烷倍半萜烯,三氯cadinin A,分离自从海洋红藻表面获得的维氏木霉Y13-3的培养物。通过解释1D / 2D NMR和MS数据明确分配了它们的结构和相对构型,并通过X射线衍射或借助量子化学计算的ECD光谱确定了它们的绝对构型。这些化合物代表丝状真菌中两种罕见的倍半萜烯类型,其中六种具有对某些海洋浮游生物的有效抑制作用。

更新日期:2018-08-27
down
wechat
bug