Abstract In this study, a highly sensitive enzyme-free glucose sensor was constructed by Ni3S2 nanomaterials compounded with ionic liquid functionalized graphene (IL-graphene). The structure of the Ni3S2/IL-graphene nanocomposites was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The electrochemical properties of this enhanced material towards glucose detection were studied by cyclic voltammetry (CV) and amperometric methods. In comparison with the bare glassy carbon electrode (GCE) and the IL-graphene/GCE, the Ni3S2/IL-graphene/GCE showed significant electrocatalytic activity for glucose oxidation. A wide linear range of 0–500 μM was obtained with a sensitivity of 25.343 μA μM−1 cm−1 as well as a detection limit of 0.161 μM (S/N = 3). Some interferences with glucose, such as dopamine, lactose, uric acid and ascorbic acid, have been considered in the presence of glucose on Ni3S2/IL-graphene/GCE. The results showed that there was no significant change in the current response of glucose (50 μM), which indicates its strong anti-interference ability. Further, the sensor was successfully applied to the detection of glucose in fetal bovine serum.

中文翻译：

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Ni3S2/离子液体功能化石墨烯作为非酶检测葡萄糖的增强材料

摘要 本研究采用Ni3S2纳米材料与离子液体功能化石墨烯（IL-graphene）复合构建了一种高灵敏度的无酶葡萄糖传感器。Ni3S2/IL-石墨烯纳米复合材料的结构通过扫描电子显微镜（SEM）、透射电子显微镜（TEM）、X射线衍射（XRD）和X射线光电子能谱（XPS）表征。通过循环伏安法 (CV) 和电流分析法研究了这种增强材料对葡萄糖检测的电化学性质。与裸玻碳电极 (GCE) 和 IL-石墨烯/GCE 相比，Ni3S2/IL-石墨烯/GCE 显示出显着的葡萄糖氧化电催化活性。获得了 0–500 μM 的宽线性范围，灵敏度为 25.343 μA μM-1 cm-1，检测限为 0.161 μM (S/N = 3)。在 Ni3S2/IL-graphene/GCE 上存在葡萄糖时，已经考虑了对葡萄糖的一些干扰，例如多巴胺、乳糖、尿酸和抗坏血酸。结果表明，葡萄糖（50 μM）的电流响应没有明显变化，说明其抗干扰能力强。此外，该传感器还成功应用于胎牛血清中葡萄糖的检测。