Co/Co‐N nanoparticles incorporated nitrogen‐doped nanoporous carbon (Co/Co‐N@NPC) nanostructures were fabricated via pyrolysis of metal organic framework, ZIF‐67, under argon atmosphere. The ZIF‐67 derived Co/Co‐N@NPC modified carbon paste electrode exhibited excellent performance during electroanalysis of dopamine, displaying two linear ranges; 10 nM to 50 μM, and 50 μM–500 μM with sensitivity of 12.4±0.3 μA/μM/cm² and11.69±0.06 μA/μM/cm², respectively. The modified electrodes were observed to be highly selective towards dopamine even in presence of other interfering biomolecules such as ascorbic acid, glucose and uric acid. To the best of our knowledge, the sensing ability of Co/Co‐N@NPC with a lower limit of detection as 6 nM is the best compared to the previously reported cobalt mediated sensors for dopamine. Practical feasibility of the sensor was demonstrated in real sample analysis of dopamine measurement in human urine samples and dopamine hydrochloride injection samples.

中文翻译：

---

ZIF-67衍生的Co / Co-N @纳米多孔碳：一种高灵敏度和选择性的电化学多巴胺传感器

掺有氮掺杂纳米多孔碳（Co / Co-N @ NPC）的Co / Co-N纳米颗粒是通过在氩气气氛下对金属有机骨架ZIF-67进行热解而制得的。ZIF-67衍生的Co / Co-N @ NPC改性碳糊电极在多巴胺电分析过程中表现出出色的性能，显示出两个线性范围。10 nM至50μM，以及50 μM–500μM，灵敏度分别为12.4± 0.3μA /μM/ cm ^2和11.69±0.06μA/μM/ cm ²， 分别。观察到修饰电极对多巴胺具有高度选择性，即使在存在其他干扰生物分子（例如抗坏血酸，葡萄糖和尿酸）的情况下也是如此。据我们所知，与先前报道的钴介导的多巴胺传感器相比，Co / Co-N @ NPC的检测能力最低，检测限为6 nM，是最好的。该传感器的实际可行性在人体尿液样本和盐酸多巴胺注射液样本中的多巴胺测量的真实样本分析中得到了证明。