Abstract A new nanocomposite, zirconium dioxide nanoparticles decorated poly(diallyldimethylammonium chloride)-functionalized graphene (ZrO2-PDDA-Gr), was successfully synthesized through a simple and green method. The simultaneous reduction of grapheme oxide (GO) and formation of ZrO2 to produce the ZrO2-PDDA-Gr had been achieved under hydrothermal conditions. The ZrO2-PDDA-Gr showed excellent conductivity and strong adsorption ability toward Diosmin and thus was used to be an excellent probe for electrochemical sensing. The electrochemical characteristics of Diosmin were studied in detail and some dynamics parameters of electrode process were also calculated to discuss the reaction mechanism. Under the optimized conditions, a lower detection limit of 2 × 10−9 mol L−1 (S/N = 3) and a wide linear detection range from 5 × 10−9 to 2 × 10−6 mol L−1 were achieved by differential pulse voltammetry (DPV). Additionally, the proposed electroanalytical methodology was applied in fresh lemon leaves and tablets with satisfactory results, showing that fabricated sensor has potential in application.

中文翻译：

---

Diosmin的电化学行为及其对ZrO2-NPs包覆的聚（二烯丙基二甲基氯化铵）功能化石墨烯修饰电极的灵敏测定

摘要 通过一种简单、绿色的方法成功合成了一种新型纳米复合材料，二氧化锆纳米粒子修饰的聚（二烯丙基二甲基氯化铵）功能化石墨烯（ZrO2-PDDA-Gr）。在水热条件下实现了氧化石墨烯 (GO) 的同时还原和 ZrO2 的形成以生产 ZrO2-PDDA-Gr。ZrO2-PDDA-Gr 表现出优异的导电性和对 Diosmin 的强吸附能力，因此被用作电化学传感的优良探针。详细研究了地奥司明的电化学特性，计算了电极过程的一些动力学参数，讨论了反应机理。在优化条件下，通过差分脉冲伏安法实现了 2 × 10−9 mol L−1 (S/N = 3) 的检测下限和从 5 × 10−9 到 2 × 10−6 mol L−1 的宽线性检测范围（ DPV）。此外，所提出的电分析方法应用于新鲜柠檬叶和片剂，结果令人满意，表明制造的传感器具有应用潜力。