Diclofenac is a pharmaceutical compound which is listed as a priority substance to be removed from wastewater. The current research investigated the adsorption of diclofenac using graphene oxide (GO) which was characterized by Fourier transform infrared, scanning electron microscopy, X-ray diffraction, transmission electron microscopy and Raman spectroscopy. Response surface methodology was employed to optimize the adsorption of diclofenac onto GO based on central-composite design. According to the developed model, the dominant parameters affecting the process were dosage and initial concentration. The optimum adsorption conditions were dosage of 0.16 g/L, time of 14.75 min, initial concentration of 400 mg/L and temperature of 40°C. Under these conditions, GO exhibited a maximum adsorption capacity of 653.91 mg/g for diclofenac. The diclofenac uptake by GO was consistent with the Langmuir adsorption and pseudo-second-order kinetic models. The active binding sites for diclofenac in GO might be hydroxyl, carboxyl and alkoxy as determined by FTIR analysis. The results provided sufficient evidence to support GO as a promising adsorbent for removal of diclofenac in aqueous solution.

双氯芬酸是一种药物化合物，被列为要从废水中去除的优先物质。目前的研究研究了使用氧化石墨烯（GO）吸附双氯芬酸的方法，该方法以傅里叶变换红外光谱，扫描电子显微镜，X射线衍射，透射电子显微镜和拉曼光谱为特征。基于中心复合设计，采用响应表面方法优化了双氯芬酸在GO上的吸附。根据开发的模型，影响该过程的主要参数是剂量和初始浓度。最佳吸附条件为剂量为0.16 g / L，时间为14.75 min，初始浓度为400 mg / L，温度为40。℃。在这些条件下，GO对双氯芬酸的最大吸附容量为653.91 mg / g。GO对双氯芬酸的吸收与Langmuir吸附和拟二级动力学模型一致。通过FTIR分析确定，GO中双氯芬酸的活性结合位点可以是羟基，羧基和烷氧基。该结果提供了足够的证据来支持GO作为用于去除水溶液中双氯芬酸的有前途的吸附剂。