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Preparation of gold nanoparticles supported on graphene oxide with flagella as the template for nonenzymatic hydrogen peroxide sensing
Analytical and Bioanalytical Chemistry ( IF 4.3 ) Pub Date : 2018-07-10 , DOI: 10.1007/s00216-018-1206-4
Chunyuan Tian , Shuang Zhang , Xuming Zhuang , Haihua Wang , Dandan Chen , Feng Luan , Tao He , Wei He , Yang Qiu

Gold nanoparticles supported on graphene oxide with flagella as the template were developed as an electrochemical sensor for the detection of hydrogen peroxide (H2O2) in serum. The flagella–Au nanoparticles composite and graphene oxide were dropped onto a glassy carbon electrode (GCE) to form a new H2O2 electrochemical sensor. The structure morphology of the prepared sensor was characterized by transmission electron microscopy (TEM), and the electrocatalytic performance towards H2O2 reduction was evaluated by cyclic voltammetry (CV) and amperometric methods. The response current of the sensor showed a good linear relationship with the concentration of H2O2 in the range of 10–1000 μM (R2 = 0.9916). The minimum detection limit of 1 μM was obtained (S/N = 3). Finally, the sensor was applied to the detection of H2O2 in serum, and the recoveries were satisfactory. As the sensor is sensitive, fast, and easy to make, it is expected to be used for rapid detection of H2O2.

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中文翻译:

以鞭毛为模板,以氧化石墨烯为载体的金纳米颗粒的制备,用于非酶法过氧化氢感测

开发了以鞭毛为模板负载在氧化石墨烯上的金纳米颗粒作为电化学传感器,用于检测血清中的过氧化氢(H 2 O 2)。将鞭毛-Au纳米颗粒复合材料和氧化石墨烯滴到玻璃碳电极(GCE)上,以形成新的H 2 O 2电化学传感器。通过透射电镜(TEM)表征了所制备传感器的结构形态,并通过循环伏安法(CV)和安培法评估了其对H 2 O 2还原的电催化性能。传感器的响应电流与H 2 O的浓度呈良好的线性关系。2的范围为10–1000μM(R 2  = 0.9916)。获得的最小检出限为1μM(S / N  = 3)。最后,将该传感器用于血清中H 2 O 2的检测,回收率令人满意。由于该传感器灵敏,快速且易于制造,因此有望用于H 2 O 2的快速检测。

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更新日期:2018-07-10
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