The cleavage of C–C bonds has been a great challenge owing to their thermodynamic and kinetic stability. To date, the progress made in this area has mainly relied on the reaction of small rings, which is driven by releasing ring strain. Encouragingly, more and more examples of the cleavage of non-strained C–C bonds have been reported. This review provides a comprehensive overview of the transition-metal-catalyzed C–C bond activation of relatively stable and unstrained molecules that involves the formation of organometallic intermediates. In the first section we focus on the C–C bond activation achieved through β-carbon elimination, and in the second section the oxidative addition of the C–C bond to low-valent metal is summarized in detail.

中文翻译：

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涉及有机金属中间体的未应变C–C键的催化活化

由于C–C键的热力学和动力学稳定性，其裂解一直是一个巨大的挑战。迄今为止，该领域的进展主要依靠小环的反应，这是由释放环应变驱动的。令人鼓舞的是，越来越多的例子报道了非应变CC键断裂的例子。这篇综述对过渡金属催化的相对稳定且不受应变的分子的C–C键活化进行了全面概述，其中涉及有机金属中间体的形成。在第一部分中，我们重点介绍通过消除β-碳所实现的C–C键活化，在第二部分中，详细概述了C–C键向低价金属的氧化加成。