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Iron‐Catalyzed Synthesis of Substituted Thiazoles from Enamines and Elemental Sulfur through C−S Bond Formation
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2018-09-04 , DOI: 10.1002/adsc.201800693
Mingzhong Wu 1 , Yong Jiang 2 , Zhenyu An 1 , Zhenjie Qi 1 , Rulong Yan 1
Affiliation  

An atom economical approach for the synthesis of substituted thiazoles starting from enamines and elemental sulfur through the C−H functionalization/C−S bond formation is described. Under the optimized conditions, various substituted enamines reacted smoothly with elemental sulfur and the desired substituted thiazoles were generated in moderate to excellent yields.

中文翻译:

铁催化从烯胺和元素硫通过C-S键形成的取代噻唑合成

描述了一种原子经济的方法,用于从烯胺和元素硫开始通过CH官能化/ CS键的形成来合成取代的噻唑。在优化的条件下,各种取代的烯胺与元素硫顺利反应,并以中等至极好的收率生成了所需的取代的噻唑。
更新日期:2018-09-04
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