It is of great significance for superoxide anion (O₂^•−) detection due to its important role in regulation of biological function. The nanoscale coordination polymers (NCPs) core-shell nanostructures have attracted increasing interests for their nanosized-dependent properties. In this study, SiO₂@Tb/guanosine 5′-monophosphate (GMP) NCPs with core-shell nanostructures was designed for O₂^•− detection. The SiO₂@Tb/GMP NCPs core-shell nanostructures were produced by using SiO₂ nanoparticles (NPs) as template to control their nano-size. First, Tb³⁺ was adsorbed on the surface of SiO₂NPs by coordination with -COOH of SiO₂NPs. Then the Tb/GMP NCPs shells were grown along the surface of SiO₂NPs. The SiO₂@Tb/GMP NCPs core-shell nanostructures were characterized with scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy and Zeta potential. The resulted SiO₂@Tb/GMP NCPs core-shell nanostructures displayed strong Tb/GMP emission which decreased linearly with the increased O₂^•− concentration in the range from 5.3 nM to 6.0 μM with a limit detection of 2.18 nM. And the SiO₂@Tb/GMP NCPs core-shell nanostructures also exhibited good selectivity and high sensitivity in HEPES buffer at pH 7.4.

由于其在调节生物功能中的重要作用，因此对超氧阴离子（O ₂ ^•−）的检测具有重要意义。纳米级配位聚合物（NCPs）的核壳纳米结构因其与纳米大小有关的特性而吸引了越来越多的关注。在本研究中，设计了具有核-壳纳米结构的SiO ₂ @ Tb /鸟苷5'-单磷酸盐（GMP）NCP，用于O ₂ ^•-检测。SiO ₂ @ Tb / GMP NCPs核壳纳米结构是通过使用SiO ₂纳米颗粒（NPs）作为模板来控制其纳米尺寸而制备的。首先，通过与SiO _2的-COOH配位，将Tb ³⁺吸附在SiO ₂ NPs的表面上NP。然后沿SiO ₂ NPs表面生长Tb / GMP NCPs壳。用扫描电子显微镜，透射电子显微镜，傅立叶变换红外光谱和Zeta电位对SiO ₂ @ Tb / GMP NCPs核壳纳米结构进行了表征。所得的SiO ₂ @ Tb / GMP NCPs核壳纳米结构显示出较强的Tb / GMP发射，随着O ₂ ^•-浓度在5.3 nM至6.0μM范围内增加而线性下降，极限检测值为2.18 nM。SiO ₂ @ Tb / GMP NCPs核壳纳米结构在pH 7.4的HEPES缓冲液中也表现出良好的选择性和高灵敏度。