The study aims at identifying 1) the most sensitive compartment among plasma phospholipids, erythrocytes, and LDL for studying alpha‐linolenic acid (ALA) conversion, and 2) whether ALA incorporation and conversion is saturable after administration of ¹³C‐labeled ALA‐rich linseed oil (LO). The effect of a daily intake of 7 g nonlabeled LO (>43% w/w ALA) for 1 month after bolus administration of 7 g ¹³C‐labeled LO on day 1, and for 2 months after bolus administration of 7 g ¹³C‐labeled LO on day 1 and day 29 on ¹³C‐ALA incorporation and conversion into its higher homologs is investigated in healthy volunteers.

中文翻译：

---

1个月和2个月大剂量α-亚麻酸对健康受试者13C标签的α-亚麻酸掺入和转化的影响

该研究旨在确定1）血浆磷脂，红细胞和LDL中最敏感的区室，以研究α-亚麻酸（ALA）的转化; 2）在施用¹³ C标记的富含ALA的物质后，ALA的掺入和转化是否可饱和亚麻籽油（LO）。每日摄入7克的效果为7g推注给药后非标记LO（> 43％w / w的ALA）1个月¹³ C标记的LO在第1天，和用于为7g推注施用后2个月¹³ Ç在健康志愿者中研究了第¹³天C-ALA掺入并转化为其更高同源物的第1天和第29天标记的LO 。