Sulfonamides (SAs) and sul antibiotic resistance genes (ARGs) have been extensively detected in drinking water sources and warrant further studies on the removal of them in different drinking water treatment processes (DWTPS). The prevalence of 13 SAs, sul1, sul2 and class I integrase gene intI1 in conventional and advanced processes was investigated using HPLC-MS/MS and real-time quantitative PCR (qPCR), respectively. The most abundant SA was sulfamethoxazole, with the maximum concentration of 67.27 ng/L. High concentration of sulfamethoxazole was also measured in finished water in both conventional (22.05 ng/L) and advanced (11.24 ng/L) processes. Overall, the removal efficiency of advanced process for each SA was higher than that of conventional process, except for sulfameter. The absolute concentrations of sul1, sul2 and intI1 in raw water ranged from 1.8 × 10³ to 2.4 × 10⁵ gene abundance/mL. After treatment, the residual sul ARGs and intI1 in finished water still remained at 10² - 10⁴ gene abundance/mL. Conventional treatment units, including flocculation/sedimentation/sand filtration, played a more important role in removing sul1, sul2 and intI1 than oxidation (chlorination or ozonation) and granular activated carbon filtration treatments. Based on this work, more investigations are needed to help improve the removal of both antibiotics and ARGs in DWTPS.

在饮用水源中已广泛检测到磺胺类（SAs）和sul类抗生素抗性基因（ARGs），因此有必要进一步研究如何在不同的饮用水处理工艺（DWTPS）中去除它们。13种SA，sul1，sul2和I类整合酶intI1的患病率分别使用HPLC-MS / MS和实时定量PCR（qPCR）来研究常规方法和高级方法中的方法。SA中含量最高的是磺胺甲恶唑，最大浓度为67.27 ng / L。在常规工艺（22.05 ng / L）和高级工艺（11.24 ng / L）中，最终水中的磺胺甲恶唑的浓度也很高。总体而言，除磺化仪外，每种SA的先进工艺的去除效率均高于常规工艺。原水中sul1，sul2和intI1的绝对浓度范围为1.8×10 ³至2.4×10 ⁵基因丰度/ mL。治疗后，残余sul ARGs和intI1成品水仍保持在10 ² - 10 ⁴基因丰度/毫升。常规的处理装置，包括絮凝/沉淀/沙滤，在去除sul1，sul2和intI1方面比氧化（氯化或臭氧化）和颗粒状活性炭过滤处理更重要。基于这项工作，需要进行更多的研究以帮助改善DWTPS中抗生素和ARG的去除。