In the last decade, native mass spectrometry has emerged as a powerful tool for studying the interactions of lipids and other small molecules with integral membrane proteins and their complexes. In this issue ofCell Chemical Biology,Pyle et al. (2018)establishes the role of phosphatidyl-inositol in dimerization and activity of a eukaryotic purine transporter (UapA).

中文翻译：

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膜蛋白功能的脂质调节

在过去的十年中，天然质谱已成为研究脂质和其他小分子与完整膜蛋白及其复合物相互作用的有力工具。在本期《细胞化学生物学》中，Pyle等人。（2018）确立了磷脂酰肌醇在真核嘌呤转运蛋白（UapA）的二聚化和活性中的作用。