Bicelles are used in many membrane protein studies because they are thought to be more bilayer-like than micelles. We investigated the properties of “isotropic” bicelles by small-angle neutron scattering, small-angle X-ray scattering, fluorescence anisotropy, and molecular dynamics. All data suggest that bicelles with a q value below 1 deviate from the classic bicelle that contains lipids in the core and detergent in the rim. Thus not all isotropic bicelles are bilayer-like.

中文翻译：

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低q Bicelles是混合Micells

Bicelles被用于许多膜蛋白研究中，因为它们被认为比胶束更像双层。我们通过小角度中子散射，小角度X射线散射，荧光各向异性和分子动力学研究了“各向同性”双晶胞的性质。所有数据都表明，q值小于1的Bicell偏离了经典的Bicelle，它在核心中包含脂质，在边缘中包含清洁剂。因此，并非所有的各向同性双胞胎都是双层的。