Multiplex imaging of live breast cancer tumour models through tissue using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)†,Chemical Communications

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Multiplex imaging of live breast cancer tumour models through tissue using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)†
Chemical Communications ( IF 4.9 ) Pub Date : 2018-07-16 00:00:00 , DOI: 10.1039/c8cc04267e
Fay Nicolson _{1,

2,

3,

4} , Lauren E. Jamieson _{1,

2,

3,

4} , Samuel Mabbott _{1,

2,

3,

4} , Konstantinos Plakas _{5,

6,

7,

8,

9} , Neil C. Shand _{4,

10,

11} , Michael R. Detty _{5,

6,

7,

8,

9} , Duncan Graham _{1,

2,

3,

4} , Karen Faulds _{1,

2,

3,

4}

Affiliation

Through utilizing the depth penetration capabilities of SESORS, multiplexed imaging and classification of three singleplex nanotags and a triplex of nanotags within breast cancer tumour models is reported for the first time through depths of 10 mm using a handheld SORS instrument.

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