Photobiomodulation (PBM) is a treatment method based on research findings showing that irradiation with certain wavelengths of red or near-infrared light has been shown to produce a range of physiological effects in cells, tissues, animals and humans. Scientific research into PBM was initially started in the late 1960s by utilizing the newly invented (1960) lasers, and the therapy rapidly became known as “low-level laser therapy”. It was mainly used for wound healing and reduction of pain and inflammation. Despite other light sources being available during the first 40 years of PBM research, lasers remained by far the most commonly employed device, and in fact, some authors insisted that lasers were essential to the therapeutic benefit. Collimated, coherent, highly monochromatic beams with the possibility of high power densities were considered preferable. However in recent years, non-coherent light sources such as light-emitting diodes (LEDs) and broad-band lamps have become common. Advantages of LEDs include no laser safety considerations, ease of home use, ability to irradiate a large area of tissue at once, possibility of wearable devices, and much lower cost per mW. LED photobiomodulation is here to stay.

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光生物调制：激光与发光二极管？†

光生物调节（PBM）是一种基于研究结果的治疗方法，该研究结果表明，已证明使用某些波长的红色或近红外光进行照射会在细胞，组织，动物和人类中产生一系列生理效应。PBM的科学研究始于1960年代末，是利用新发明的（1960）激光器进行的，该疗法迅速被称为“低水平激光疗法”。它主要用于伤口愈合以及减轻疼痛和炎症。尽管在PBM研究的前40年中还可以使用其他光源，但是激光仍然是迄今为止最常用的设备，实际上，一些作者坚持认为激光对于治疗效果至关重要。准直，连贯，具有高功率密度可能性的高度单色光束被认为是优选的。然而，近年来，诸如发光二极管（LED）和宽带灯的非相干光源已经变得普遍。LED的优点包括无需考虑激光安全性，易于家庭使用，能够一次照射大面积组织的能力，可穿戴设备的可能性以及每mW成本低得多的优点。LED光生物调节将继续存在。