Nucleophilic addition of organometallic reagents to ketimines and hydrazones can be a challenging transformation. Here we report the use of fluorenone-derived mixed azines which promote facile addition of Grignard reagents. The fluorenylidene activating group is easily installed and removed, thereby offering practical access to highly substituted amines and hydrazines.

中文翻译：

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芴基活化基团能够将简单的格氏试剂添加到 C=N 亲电试剂中

有机金属试剂与酮亚胺和腙的亲核加成是一个具有挑战性的转化。在这里，我们报告了芴酮衍生的混合吖嗪的使用，它促进了格氏试剂的轻松添加。芴基活化基团很容易安装和去除，从而为获得高度取代的胺和肼提供了实用的途径。