A pH‐sensitive sodium biosensor: In vitro selection yielded a mutant of a previously reported sodium‐specific DNAzyme with a slightly acidic pH optimum and the same excellent specificity for Na⁺. It was engineered into a fluorescent Na⁺ biosensor with a detection limit of 223 μm Na⁺ by attaching a fluorophore/quencher pair. Preliminary detection of Na⁺ in serum was demonstrated.

中文翻译：

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在弱酸性条件下对Na +具有高度特异性的体外选择的DNAzyme突变体

pH敏感的钠生物传感器：体外选择产生了先前报道的钠特异性DNA酶的突变体，其酸性稍弱，pH最佳，并且对Na ⁺具有相同的优异特异性。它被工程化到荧光的Na ⁺的生物传感器用的223μ的检测极限中号的Na ⁺通过将荧光团/猝灭剂对。证明了血清中Na ^+的初步检测。