当前位置: X-MOL 学术J. Chromatogr. A › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Enantiomeric ratios: Why so many notations?
Journal of Chromatography A ( IF 4.1 ) Pub Date : 2018-07-11 , DOI: 10.1016/j.chroma.2018.07.039
Maria E. Tiritan , Carla Fernandes , Alexandra S. Maia , Madalena Pinto , Quezia B. Cass

The correct quantification of enantiomers is pivotal in a variety of fields, such as pharmacokinetic studies, enantioselective syntheses, chemical characterization of natural products, authentication of fragrance and food, biodegradation behavior, accurate evaluation of environmental risk, and it can also provide information for sentencing guidance in forensic field. Enantioselective chromatography is the first choice to assess the composition of an enantiomeric mixture. Different notations have been used to express the measured enantiomeric ratios, which compromise the results and represent a challenge for data comparison. This manuscript critically discusses the currently used notations and exemplifies with applications in different fields indicating the advantages and disadvantages of one of the adopted systems. In order to simplify the notations, the use of enantiomeric ratio (e.r.%) as standardization for nonchiroptical methods is proposed.



中文翻译:

对映体比率:为什么要使用这么多的符号?

对映体的正确定量在许多领域至关重要,例如药代动力学研究,对映选择性合成,天然产物的化学表征,香料和食品的鉴定,生物降解行为,对环境风险的准确评估,它还可以为判决提供信息。法医领域的指导。对映选择性色谱法是评估对映体混合物组成的首选方法。已经使用了不同的符号来表示测得的对映体比率,这损害了结果并代表了数据比较的挑战。该手稿批判性地讨论了当前使用的符号,并举例说明了不同领域的应用,指出了所采用系统之一的优缺点。

更新日期:2018-07-11
down
wechat
bug