During the past few years, graphene oxide (GO) becomes increasingly significant in fluorescent biosensing due to its unique heterogeneous structure that offers it potential applications in various fields. Based on the transformation of affinities between GO and DNA, plenty of assays for bioanalysis have been developed rapidly, in which GO generally functions as a quencher. In this review, the current status and design mechanism of fluorescent biosensing platform based on graphene oxide-DNA are introduced in detail; the latest research progress of biomolecular fluorescence sensing has been summarized, classified and compared in this paper. Some unique and elegant ideas are introduced.

在过去的几年中，氧化石墨烯（GO）由于其独特的异质结构而在荧光生物传感中变得越来越重要，这为其在各种领域中的潜在应用提供了可能。基于GO和DNA之间亲和力的转变，已经迅速开发出许多用于生物分析的测定方法，其中GO通常起淬灭剂的作用。本文详细介绍了基于氧化石墨烯-DNA的荧光生物传感平台的现状和设计机理。本文对生物分子荧光传感的最新研究进展进行了总结，归类和比较。介绍了一些独特而优雅的想法。