Abstract

Synergistic bimetallic catalysis has become a very efficient tool for the selective carboboration of unsaturated hydrocarbons. This synthetic approach is based on the use of a catalytically generated boron-substituted organocopper nucleophile in a cross-coupling reaction catalyzed by a second transition metal. This way, hydrocarbons can be used as pro-nucleophiles in this type of transformations thus rendering a clean and operationally simple alternative to the traditional cross-coupling methodologies. This review provides a summary of the developments on this topic and discusses both the synthetic utility and mechanisms of these reactions.

1 Introduction

2 Carboboration of Alkenes via Synergistic Catalysis

3 Carboboration of 1,3-Dienes via Synergistic Catalysis

4 Carboboration of Alkynes via Synergistic Catalysis

5 Conclusions

Synergistic bimetallic catalysis has become a very efficient tool for the selective carboboration of unsaturated hydrocarbons. This synthetic approach is based on the use of a catalytically generated boron-substituted organocopper nucleophile in a cross-coupling reaction catalyzed by a second transition metal. This way, hydrocarbons can be used as pro-nucleophiles in this type of transformations thus rendering a clean and operationally simple alternative to the traditional cross-coupling methodologies. This review provides a summary of the developments on this topic and discusses both the synthetic utility and mechanisms of these reactions.

1 Introduction

2 Carboboration of Alkenes via Synergistic Catalysis

3 Carboboration of 1,3-Dienes via Synergistic Catalysis

4 Carboboration of Alkynes via Synergistic Catalysis

5 Conclusions

中文翻译：

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协同双金属催化不饱和烃的碳硼化

摘要

协同双金属催化已经成为用于不饱和烃的选择性碳硼化的非常有效的工具。该合成方法基于在第二过渡金属催化的交叉偶联反应中催化生成的硼取代的有机铜亲核试剂的使用。这样，在这种类型的转化中，碳氢化合物可用作亲核亲原体，从而提供了一种清洁且操作简单的替代方法，可替代传统的交叉偶联方法。这篇综述总结了该主题的发展，并讨论了这些反应的合成效用和机理。

1引言

2通过协同催化对烯烃进行碳硼化

3通过协同催化对1,3-二烯进行碳硼化

4通过协同催化对炔烃进行碳硼化

5。结论

协同双金属催化已经成为用于不饱和烃的选择性碳硼化的非常有效的工具。该合成方法基于在第二过渡金属催化的交叉偶联反应中催化生成的硼取代的有机铜亲核试剂的使用。这样，在这种类型的转化中，碳氢化合物可用作亲核亲原体，从而提供了一种清洁且操作简单的替代方法，可替代传统的交叉偶联方法。这篇综述总结了该主题的发展，并讨论了这些反应的合成效用和机理。

1引言

2通过协同催化对烯烃进行碳硼化

3通过协同催化对1,3-二烯进行碳硼化

4通过协同催化对炔烃进行碳硼化

5。结论