AbstractGraphene nanosheets (GSs) were prepared via liquid-phase non-covalent exfoliation of graphite powder in N,N-dimethylformamide under the assistance of copper(II) meso-tetra(4-carboxyphenyl)porphyrin tetrasodium salt Na4(CuTCPP). A glassy carbon electrode (GCE) was modified with a film of such GSs which, due to the good electrical conductivity of graphene and the electrocatalytic properties of Na4(CuTCPP), is capable of simultaneous determination of acetaminophen (AC) and dopamine (DA). The peak currents, best measured at voltage of 0.2 V (for DA) and 0.4 V (for AC; both vs. SCE), increase linearly in the 0.0024–3.6 μM and 0.004–7.6 μM concentration ranges, respectively. The detection limits are 0.8 nM for DA and 0.7 nM for AC. The sensor was successfully applied to the simultaneous determination of AC and DA in pharmaceutical preparations and spiked human serum. The results were in good agreement with those obtained for the same samples by HPLC. Graphical abstractGraphene nanosheets were prepared via a facile liquid-phase exfoliation of graphite with the assistance of copper(II) meso-tetra(4-carboxyphenyl)porphyrin tetrasodium salt. A graphene nanosheet-film modified glassy carbon electrode was fabricated to determine acetaminophen and dopamine through a simple and effective strategy.

中文翻译：

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使用铜卟啉剥离石墨烯修饰的玻碳电极同时伏安法测定对乙酰氨基酚和多巴胺

摘要 在铜（II）内消旋四（4-羧基苯基）卟啉四钠盐 Na4（CuTCPP）的辅助下，通过石墨粉在 N,N-二甲基甲酰胺中液相非共价剥离制备石墨烯纳米片（GSs）。玻璃碳电极 (GCE) 用这种 GSs 的薄膜修饰，由于石墨烯的良好导电性和 Na4(CuTCPP) 的电催化性能，能够同时测定对乙酰氨基酚 (AC) 和多巴胺 (DA) . 峰值电流最好在 0.2 V（DA）和 0.4 V（AC；两者均与 SCE）的电压下测量，分别在 0.0024–3.6 μM 和 0.004–7.6 μM 浓度范围内线性增加。DA 的检测限为 0.8 nM，AC 的检测限为 0.7 nM。该传感器成功应用于同时测定药物制剂和加标人血清中的AC和DA。结果与通过 HPLC 获得的相同样品的结果非常一致。图形摘要石墨烯纳米片是在铜 (II) 内消旋四 (4-羧基苯基) 卟啉四钠盐的帮助下通过石墨的简便液相剥离制备的。制备石墨烯纳米片膜修饰的玻碳电极，通过简单有效的策略测定对乙酰氨基酚和多巴胺。图形摘要石墨烯纳米片是在铜 (II) 内消旋四 (4-羧基苯基) 卟啉四钠盐的帮助下通过石墨的简便液相剥离制备的。制备石墨烯纳米片膜修饰的玻碳电极，通过简单有效的策略测定对乙酰氨基酚和多巴胺。图形摘要石墨烯纳米片是在铜 (II) 内消旋四 (4-羧基苯基) 卟啉四钠盐的帮助下通过石墨的简便液相剥离制备的。制备石墨烯纳米片膜修饰的玻碳电极，通过简单有效的策略测定对乙酰氨基酚和多巴胺。