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Mesoporous silica nanoparticles in recent photodynamic therapy applications
Photochemical & Photobiological Sciences ( IF 3.1 ) Pub Date : 2018-07-06 00:00:00 , DOI: 10.1039/c8pp00143j
Sumeyra Bayir 1, 2, 3, 4, 5 , Alexandre Barras 6, 7, 8, 9, 10 , Rabah Boukherroub 6, 7, 8, 9, 10 , Sabine Szunerits 6, 7, 8, 9, 10 , Laurence Raehm 1, 2, 3, 4, 5 , Sébastien Richeter 1, 2, 3, 4, 5 , Jean-Olivier Durand 1, 2, 3, 4, 5
Affiliation  

In this review, the use of mesoporous silica nanoparticles for photodynamic therapy (PDT) applications is described for the year 2017. Since the pioneering work in 2009, nanosystems involving mesoporous silica nanoparticles have gained in complexity with a sophisticated core–shell system able to perform multi-imaging and multi-therapies, not only for cancer diseases but also for anti-microbial therapy, atherosclerosis, or Alzheimer disease. Near-infrared, excitation light based on up-converting systems, X-rays or persistent luminescent systems are described for deeper tissue treatments.

中文翻译:

介孔二氧化硅纳米粒子在最近的光动力疗法中的应用

在这篇综述中,描述了2017年将中孔二氧化硅纳米粒子用于光动力疗法(PDT)的应用。自2009年进行开创性工作以来,涉及中孔二氧化硅纳米粒子的纳米系统已经变得复杂,其复杂的核-壳系统能够执行多种成像和多种疗法,不仅适用于癌症疾病,而且还适用于抗微生物疗法,动脉粥样硬化或阿尔茨海默氏病。描述了基于上转换系统,X射线或持续发光系统的近红外激发光,用于更深层的组织治疗。
更新日期:2018-07-06
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