The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging,Food & Function

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The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging
Food & Function ( IF 6.1 ) Pub Date : 2018-07-06 , DOI: 10.1039/c8fo00956b
A. Cortés-Martín _{1,

2,

3,

4,

5} , R. García-Villalba _{1,

2,

3,

4,

5} , A. González-Sarrías _{1,

2,

3,

4,

5} , M. Romo-Vaquero _{1,

2,

3,

4,

5} , V. Loria-Kohen _{6,

7,

8,

9,

10} , A. Ramírez-de-Molina _{6,

7,

8,

9,

10} , F. A. Tomás-Barberán _{1,

2,

3,

4,

5} , M. V. Selma _{1,

2,

3,

4,

5} , J. C. Espín _{1,

2,

3,

4,

5}

Affiliation

Understanding individuals’ response to dietary bioactives is crucial for personalized nutrition. We report here for the first time in a Caucasian cohort (5–90 years, n = 839) that aging is the main factor that determines the gut microbiota involved in the ellagic acid–ellagitannin metabolism (urolithin metabotypes), with potential consequences for human health.

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