Compulsive feeding has been considered as an addicted-like behavior with similarities to drug addiction. Food intake is brain controlled involving a balance between metabolic and hedonic pathways that modulate respectively how much and what is eaten. Pathological conditions such as compulsive feeding or an eating addiction can interfere with this balance and obesity may develop. Daily feeding times are also centrally controlled by the circadian clock in the suprachiasmatic nucleus. Disruptions of this body clock (e.g., social jet-lag, shift work) lead to eating and metabolic disorders. The circadian pacemaker is intricately connected with the metabolic and hedonic centers controlling feeding, and most importantly, some of these nuclei have clock activity. When the brain circadian system is compromised in eating disorders, such perturbations may be in part the causes of compulsive feeding, night eating and addictive-like eating behavior. Therefore, food intake is regulated by the central circadian-metabolic-hedonic network, which is functionally interconnected to avoid perturbing the eating behavior physiology.

中文翻译：

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食物摄入和类似上瘾的饮食行为：是时候考虑生物钟了。

强迫性进食被认为是一种类似于吸毒成瘾的上瘾行为。食物的摄取是受大脑控制的，涉及代谢和享乐途径之间的平衡，分别调节食用量和食用量。强迫性进食或进食成瘾等病理状况可能会干扰这种平衡，并且可能会出现肥胖症。每日摄食时间也由跨眼上核中的生物钟来集中控制。人体时钟的中断（例如社交时差，轮班工作）会导致进食和代谢异常。昼夜节律起搏器与控制进食的代谢和享乐中心错综复杂，最重要的是，其中一些原子核具有时钟活动。当大脑昼夜节律系统在进食障碍中受损时，这种扰动可能部分是强迫性进食，夜间进食和上瘾的进食行为的原因。因此，食物摄入量由中央昼夜节律-代谢-享乐网络调节，该网络在功能上相互关联以避免扰乱进食行为生理。