Trends in Analytical Chemistry ( IF 13.1 ) Pub Date : 2018-07-04 , DOI: 10.1016/j.trac.2018.06.015 Ana Sanchis , J.-Pablo Salvador , M.-Pilar Marco
The present article gives an overview of the situation of the aquatic ecosystem in respect to contamination by chemical pollutants and the different multiplexed techniques used to detect, identify and quantify water pollutants. A brief comparison between chromatographic and immunochemical methods is described at the beginning of this article, as an introduction of the increasing interest for multidetection of pollutants in these environments. The information regarding multiplexed immunochemical and biosensors technologies is presented emphasizing all aspects, from the importance of the design of immunizing haptens and the production of antibodies with different specificity potentials, to the establishment of different approaches to fulfill the multiplexation needs the actual environmental monitoring requires. For each class of platforms described a brief description of the physical principle, specific features, and basic concepts is presented providing additionally specific examples.
中文翻译:
用于检测水生环境污染物的多重免疫化学技术
本文概述了有关化学污染物污染的水生生态系统状况,以及用于检测,识别和量化水污染物的不同多路复用技术。本文开头介绍了色谱和免疫化学方法之间的简要比较,以介绍人们越来越关注在这些环境中进行污染物的多重检测。有关多重免疫化学和生物传感器的信息提出了从各个方面的技术,从设计免疫半抗原的重要性和产生具有不同特异性潜能的抗体的重要性,到建立满足实际环境监测要求的多路复用需求的不同方法。对于所描述的每类平台,将提供物理原理,特定功能和基本概念的简要说明,并提供其他特定示例。